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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">meat</journal-id><journal-title-group><journal-title xml:lang="en">Theory and practice of meat processing</journal-title><trans-title-group xml:lang="ru"><trans-title>Теория и практика переработки мяса</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2414-438X</issn><issn pub-type="epub">2414-441X</issn><publisher><publisher-name>ФГБНУ «Федеральный научный центр пищевых систем им. В.М. Горбатова» РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2414-438X-2017-2-3-4-20</article-id><article-id custom-type="elpub" pub-id-type="custom">meat-68</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ANTIMICROBIAL SUBSTANCES: AN ALTERNATIVE APPROACH TO THE EXTENSION OF SHELF LIFE</article-title><trans-title-group xml:lang="ru"><trans-title>АНТИМИКРОБНЫЕ ВЕЩЕСТВА: АЛЬТЕРНАТИВНЫЙ  ПОДХОД К ПРОДЛЕНИЮ СРОКОВ ХРАНЕНИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукинова</surname><given-names>Екатерина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Lukinova</surname><given-names>Ekaterina A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший лаборант Экспериментальной клиники-лаборатории биологически активных веществ животного происхождения, Федеральный научный центр пищевых систем им. В.М. Горбатова РАН 109316, г.Москва, ул. Талалихина, 26 Тел.: +7–495–676–92–11</p></bio><bio xml:lang="en"><p>senior laboratory assistant of Experimental clinic — research laboratory of biologically active substances of an animal origin, V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences 109316, Moscow, Talalikhina str., 26 Tel.: +7–495–676–92–11</p></bio><email xlink:type="simple">kate3584@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котенкова</surname><given-names>Елена Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Kotenkova</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат технических наук, научный сотрудник Экспериментальной клиники-лаборатории биологически активных веществ животного происхождения, Федеральный научный центр пищевых систем им. В.М. Горбатова РАН 109316, г.Москва, ул. Талалихина, 26 Тел.: +7–495–676–92–11</p></bio><bio xml:lang="en"><p>candidate of technical sciences, research scientist of Experimental clinic –research laboratory of biologically active substances of an animal origin, V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences 109316, Moscow, Talalikhina str., 26 Tel.: +7–495–676–92–11</p></bio><email xlink:type="simple">lazovlena92@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаренко</surname><given-names>Александр Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Makarenko</surname><given-names>Alexander N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры гистологии и  эмбриологии Национального медицинского университета им. А.А. Богомольца 02000, г. Киев, пр. Победы, 34, морфологический корпус. Тел.: +380–454–49–89</p></bio><bio xml:lang="en"><p>doctor of medical sciences, professor of Department of histology and embryology, Bogomolets national medical university 02000, Kiev, 34 Peremohy Avenue, Morphology Building. Теl.: +380–454–49–89</p></bio><email xlink:type="simple">makarenko.alexander.1954@gmail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный научный центр пищевых систем им. В.М. Горбатова РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский университет им. А.А. Богомольца</institution><country>Украина</country></aff><aff xml:lang="en"><institution>Bogomolets National Medical University</institution><country>Ukraine</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>10</month><year>2017</year></pub-date><volume>2</volume><issue>3</issue><fpage>4</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Lukinova E.A., Kotenkova E.A., Makarenko A.N., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Лукинова Е.А., Котенкова Е.А., Макаренко А.Н.</copyright-holder><copyright-holder xml:lang="en">Lukinova E.A., Kotenkova E.A., Makarenko A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.meatjournal.ru/jour/article/view/68">https://www.meatjournal.ru/jour/article/view/68</self-uri><abstract><p>The problem of high losses of raw materials and products in the food industry is reviewed in the article. Brief lists of spoilage types as well as the available approaches to meat preservation are discussed including technological, physical and chemical. Natural antimicrobial substances are considered as alternative approaches, the existence of which has been known for more than 60 years. Antimicrobial peptides are the evolutionary ancient factor of innate immunity and are found in the cells and tissues of vertebrate and invertebrate animals, plants, fungi and bacteria. Present approaches to their classification, structure and mechanisms of action are discussed. The information from the Antimicrobial Peptide Database and the UniProt Protein Database is systematized in relation to the presence of antimicrobial substances in the tissues of pigs and cattle. Such parameters as the molecular weight, isoelectric point, charge, amino acid sequence and share a hydrophobic part, as well as a range of activities: antibacterial, antifungal, antiviral, antiparasitic, etc. are presented in the article. On the basis of the review, alternative sources of antimicrobial proteins and peptides are proposed as well as technology for shelf life prolonging.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящей статье рассмотрена проблема высоких потерь сырья и продуктов в пищевой индустрии. Представлен краткий перечень существующих причин микробиологической порчи и  подходов к  ее минимизации, включая технологические, физические и  химические. В  качестве альтернативы существующим подходам рассмотрены природные антимикробные вещества, о существовании которых известно уже более 60 лет. Антимикробные пептиды являются эволюционно древним фактором врожденного иммунитета и  обнаруживаются в  клетках и  тканях позвоночных и беспозвоночных животных, растениях, грибах и  бактериях. Представлены подходы к  их классификации, особенности строения и  механизмов действия. Систематизирована информация из ведущих мировых баз данных The Antimicrobial Peptide Database и Uni Prot Protein Database о наличии антимикробных веществ в тканях свиней и крупного рогатого скота, включая их молекулярную массу и белков-предшественников (при наличии), изоэлектрическую точку, заряд, аминокислотную последовательность и долю гидрофобной части в ней, а также спектр активности: антибактериальная, противогрибковая, противовирусная, противопаразитарная и пр. На основе проведенного обзора предложены альтернативные источники их выделения и намечена перспектива создания технологии повышения хранимоспособности пищевой продукции.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>микробиологическая порча</kwd><kwd>сроки хранения</kwd><kwd>антимикробные вещества</kwd><kwd>пептиды</kwd><kwd>белки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>microbiological spoilage</kwd><kwd>shelf life</kwd><kwd>antimicrobial substances</kwd><kwd>peptides</kwd><kwd>proteins</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено за счет гранта Российского научного фонда (проект № 17–76–10033).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Научные подходы к управлению качеством Продовольственные потери и пищевые отходы в контексте устойчивых продовольственных систем. 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