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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">meat</journal-id><journal-title-group><journal-title xml:lang="en">Theory and practice of meat processing</journal-title><trans-title-group xml:lang="ru"><trans-title>Теория и практика переработки мяса</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2414-438X</issn><issn pub-type="epub">2414-441X</issn><publisher><publisher-name>ФГБНУ «Федеральный научный центр пищевых систем им. В.М. Горбатова» РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2414-438X-2022-7-3-164-176</article-id><article-id custom-type="elpub" pub-id-type="custom">meat-226</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Systemic approach in the development of functional foods for various noncommunicable diseases</article-title><trans-title-group xml:lang="ru"><trans-title>Systemic approach in the development of functional foods for various noncommunicable diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4298-0927</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Chernukha</surname><given-names>I. M.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernukha</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="en"><p>Irina M. Chernukha, Doctor of Technical Sciences, Professor, Academician of the Russian Academy of Sciences, Head of the Department for Coordination of Initiative and International Projects</p><p>26, Talalikhina, 109316, Moscow</p><p>Tel: +7–495–676–95–11 (109)</p></bio><email xlink:type="simple">imcher@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8313-4105</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Nikitina</surname><given-names>M. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Marina A. Nikitina, Doctor of Technical Sciences, Docent, Leading Scientific Worker, the Head of the Direction of Information Technologies of the Center of Economic and Analytical Research and Information Technologies</p><p>26, Talalikhina, 109316, Moscow</p><p>Tel: +7–495–676–95–11 (297)</p></bio><email xlink:type="simple">m.nikitina@fncps.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2831-4864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Aslanova</surname><given-names>M. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Aslanova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Marietta A. Aslanova, Candidate of Technical Sciences, Leading Research Scientist</p><p>26, Talalikhina str., 109316, Moscow</p><p>Tel: +7–495–676–95–11 (263)</p></bio><email xlink:type="simple">m.aslanova@fncps.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2193-0624</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Qusay</surname><given-names>A. T.</given-names></name><name name-style="western" xml:lang="en"><surname>Qusay</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="en"><p>Abu T. Qusay, Postgraduate Student</p><p>33, Talalikhina, 109316, Moscow</p><p>Tel: +7–499–750–01–11(6015)</p></bio><email xlink:type="simple">qusay2077@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>V. M. Gorbatov Federal Research Center for Food Systems</institution><country>Russian Federation</country></aff><aff xml:lang="en" id="aff-2"><institution>Moscow State University of Food Production; University of Hama</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2022</year></pub-date><volume>7</volume><issue>3</issue><fpage>164</fpage><lpage>176</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Chernukha I.M., Nikitina M.A., Aslanova M.A., Qusay A.T., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Chernukha I.M., Nikitina M.A., Aslanova M.A., Qusay A.T.</copyright-holder><copyright-holder xml:lang="en">Chernukha I.M., Nikitina M.A., Aslanova M.A., Qusay A.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.meatjournal.ru/jour/article/view/226">https://www.meatjournal.ru/jour/article/view/226</self-uri><abstract><p>The article presents a hierarchy of requirements necessary for the successful design of food products with given composition and properties considering age restrictions and various diseases. The need for generalization and systematization of scientifically based principles, specific medical and biological requirements for food products, diets for the most common nutritional diseases in the knowledge base is shown. Using the k-means cluster analysis method, 1) meat raw materials were analyzed for inclusion in functional food for gerodietetic nutrition according to the most significant descriptors (protein, methionine + cystine amino acids, tryptophan), 2) spicy herbs and spices were analyzed for inclusion in the Muhammara recipe as natural antioxidant sources according to the descriptor of antioxidant properties. Using the example of the Muhammara recipe change, all stages of a systemic approach in the development of functional foods are shown. The first stage is related to obtaining information from the knowledge base about scientifically based nutritional principles and specific biomedical requirements for the given age group. At the second stage, the clustering of raw materials of animal and vegetable origin is carried out in order to reasonably include in the recipe of food product being developed. At the third stage, a system of balance linear algebraic equations for the chemical composition of the food product being developed (mass fraction of fat, protein, water, carbohydrates, vitamins, macro- and microelements, amino acids, etc.) is formed. The fourth stage is associated with the establishment of the target function (optimization criterion), and restrictions for recipe and balance. At the fifth stage, the problem is solved using a high-level language in a modern programming environment. At the final (sixth) stage, the nutritional value of the optimal balanced recipe is analyzed considering the target function and the given restrictions. As a result, we receive a modified Muhammara recipe with optimized protein: fat ratio. Mathematical simulation was carried out using the R Studio software with open-source lpSolve and lpSolveAPI libraries.</p></abstract><kwd-group xml:lang="en"><kwd>nutrition</kwd><kwd>functional foods</kwd><kwd>gerodietetics</kwd><kwd>knowledge base</kwd><kwd>nutritional diseases</kwd><kwd>clustering</kwd><kwd>dendrogram</kwd><kwd>simulation</kwd><kwd>tree structure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chernukha, I.M., Fedulova, L.V., Dydykin, A.S. (2014). Safe and useful products as the main factor determining the quality of life. Vsyo o Myase, 2, 20–22. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Chernukha, I.M., Fedulova, L.V., Dydykin, A.S. (2014). Safe and useful products as the main factor determining the quality of life. Vsyo o Myase, 2, 20–22. 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