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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">meat</journal-id><journal-title-group><journal-title xml:lang="en">Theory and practice of meat processing</journal-title><trans-title-group xml:lang="ru"><trans-title>Теория и практика переработки мяса</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2414-438X</issn><issn pub-type="epub">2414-441X</issn><publisher><publisher-name>ФГБНУ «Федеральный научный центр пищевых систем им. В.М. Горбатова» РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2414-438X-2020-5-2-12-19</article-id><article-id custom-type="elpub" pub-id-type="custom">meat-136</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Biologically active peptides of meat and meat product proteins: a review. Part 2. Functionality of meat bioactive peptides</article-title><trans-title-group xml:lang="ru"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4298-0927</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Chernukha</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="en"><p>Irina M. Chernukha —  doctor of technical sciences, professor, Academician of Russian Academy of Sciences, principal research scientist, Experimental clinic-laboratory «Biologically active substances of animal origin»</p><p>109316, Moscow, Talalikhina str., 26. </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9287-0585</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Mashentseva</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="en"><p>Natal’ya G. Mashentseva —  doctor of technical sciences, professor RAS, head of the Department of Biotechnology and Technology of Products of Bioorganic Synthesis</p><p>125080, Moscow, Volokolamskoe sh., 11</p></bio><email xlink:type="simple">natali-mng@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7463-4503</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Afanasev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Dmitrii A. Afanas’ev —  student, Institute of Innovative Technologies and Bioindustry of Food Products</p><p>125080, Moscow, Volokolamskoe sh., 11</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9395-705X</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Vostrikova</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="en"><p>Natal’ya L. Vostrikova —  doctor of technical sciences, head of laboratory «Center for food and feed testing»</p><p>109316, Moscow, Talalikhina str., 26</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>V.M. Gorbatov Federal Research Center for Food Systems of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff><aff xml:lang="en" id="aff-2"><institution>Moscow State University of Food Production</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>31</day><month>07</month><year>2020</year></pub-date><volume>5</volume><issue>2</issue><fpage>12</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Chernukha I.M., Mashentseva N.G., Afanasev D.A., Vostrikova N.L., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Chernukha I.M., Mashentseva N.G., Afanasev D.A., Vostrikova N.L.</copyright-holder><copyright-holder xml:lang="en">Chernukha I.M., Mashentseva N.G., Afanasev D.A., Vostrikova N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.meatjournal.ru/jour/article/view/136">https://www.meatjournal.ru/jour/article/view/136</self-uri><abstract><p>Biologically active peptides (BAP) are regarded as the main products of protein hydrolysis. BAP activity depends on the amino acid sequence molecular weight and chain length, type and charge of an amino acid at the N-terminus and C-terminus, hydrophobic and hydrophilic properties, spatial structure. They positively influence many systems of the human body, including the blood circulatory, nervous, immune, gastrointestinal and other systems. The health-improving effect of bioactive peptides is formed due to their antioxidant, antihypertensive, antithrombotic, immunomodulatory, antimicrobial, anti-allergic, opioid, anti-inflammatory, hypocholesterolemic and anticancer properties. Angiotensin-I-converting enzyme (ACE) inhibitory peptides are most studied due to their effect on blood pressure regulation. Unlike synthetic preparations, biologically active peptides do not have side effects and, therefore, can be used as their alternative. There is a growing commercial interest in peptides generated from meat proteins is in the context of health saving functional foods. The paper describes prospects, pros and cons of using bioactive peptides as functional food ingredients and biologically active food additives.</p></abstract><kwd-group xml:lang="en"><kwd>biologically active peptides</kwd><kwd>meat proteins</kwd><kwd>the functionality</kwd><kwd>ACE-I</kwd><kwd>antioxidant activity</kwd><kwd>antithrombotic activity</kwd><kwd>antimicrobial activity</kwd><kwd>anticancer effect</kwd><kwd>opioid effect</kwd><kwd>bioavailability</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The study was financed by the grant of the Russian Scientific Foundation (Project No.16–16–10073П) and the Program of the fundamental scientific research of the state academies of sciences 013.20.05</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hayes, M., Stanton, C., Fitzgerald, G.F., Ross, R.P. (2007). 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